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Blimp-1 promotes terminal differentiation of virus-specific CD8 T cells and represses the acquisition of central memory T cell properties
During acute infections, a small population of effector CD8 T cells evades terminal differentiation and survives as long-lived memory T cells. We demonstrate that the transcriptional repressor Blimp-1 enhances the formation of terminally differentiated CD8 T cells during LCMV infection, and Blimp-1...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783637/ https://ncbi.nlm.nih.gov/pubmed/19664941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.05.014 |
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