Analysis of Families with Lynch Syndrome Complicated by Advanced Serrated Neoplasia: The Importance of Pathology Review and Pedigree Analysis

The identification of Lynch syndrome has been greatly assisted by the advent of tumour immunohistochemistry (IHC) for mismatch repair (MMR) proteins, and by the recognition of the role of acquired somatic BRAF mutation in sporadic MMR-deficient colorectal cancer (CRC). However, somatic BRAF mutation...

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Huvudupphovsmän: Walsh, Michael D, Buchanan, Daniel D, Walters, Rhiannon, Roberts, Aedan, Arnold, Sven, McKeone, Diane, Clendenning, Mark, Ruszkiewicz, Andrew R, Jenkins, Mark A, Hopper, John L, Goldblatt, Jack, George, Jillian, Suthers, Graeme K, Phillips, Kerry, Young, Graeme P, Macrae, Finlay, Drini, Musa, Woods, Michael O, Parry, Susan, Jass, Jeremy R, Young, Joanne P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783449/
https://ncbi.nlm.nih.gov/pubmed/19241144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-009-9238-8
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