Analysis of Families with Lynch Syndrome Complicated by Advanced Serrated Neoplasia: The Importance of Pathology Review and Pedigree Analysis

The identification of Lynch syndrome has been greatly assisted by the advent of tumour immunohistochemistry (IHC) for mismatch repair (MMR) proteins, and by the recognition of the role of acquired somatic BRAF mutation in sporadic MMR-deficient colorectal cancer (CRC). However, somatic BRAF mutation...

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Detalhes bibliográficos
Main Authors: Walsh, Michael D, Buchanan, Daniel D, Walters, Rhiannon, Roberts, Aedan, Arnold, Sven, McKeone, Diane, Clendenning, Mark, Ruszkiewicz, Andrew R, Jenkins, Mark A, Hopper, John L, Goldblatt, Jack, George, Jillian, Suthers, Graeme K, Phillips, Kerry, Young, Graeme P, Macrae, Finlay, Drini, Musa, Woods, Michael O, Parry, Susan, Jass, Jeremy R, Young, Joanne P
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783449/
https://ncbi.nlm.nih.gov/pubmed/19241144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-009-9238-8
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