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Signal Amplification of Target Protein on Heparin Glycan Microarray

A heparin glycan chip (HepGlyChip) with 4800-fold enhanced signal-to-noise ratio as compared to the control without heparin was developed for high-throughput analysis of heparin-protein interactions for new drug development and for the screening biological samples in diagnostic applications. As a pr...

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Detalhes bibliográficos
Main Authors: Park, Tae-Joon, Lee, Moo-Yeal, Dordick, Jonathan S., Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783401/
https://ncbi.nlm.nih.gov/pubmed/18722996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.07.037
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