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Ricin A-chain requires c-Jun N-terminal kinase to induce apoptosis in nontransformed epithelial cells
Ricin is a toxin isolated from castor beans that has potential as a weapon of bioterrorism. This glycoprotein consists of an A-chain (RTA) that damages the ribosome and inhibits protein synthesis and a B-chain that plays a role in cellular uptake. Ricin activates the c-Jun N-terminal kinase (JNK) an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783365/ https://ncbi.nlm.nih.gov/pubmed/19695342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2009.08.007 |
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