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LSC Stem/Progenitors Are Tumor Initiating Cells in the Pten Null Prostate Cancer Model

We have previously demonstrated that Pten deletion leads to the expansion of subset of prostate cancer cells positive for CK5 and p63 (1). While this subpopulation may be involved in tumor initiation or progression, studies to date have not functionally validated this hypothesis. Using in vitro sphe...

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Detalhes bibliográficos
Main Authors: Mulholland, David J, Xin, Li, Morim, Ashkan, Lawson, Devon, Witte, Owen, Wu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783355/
https://ncbi.nlm.nih.gov/pubmed/19887604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4673
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