Lung Adenocarcinoma with EGFR Amplification has Distinct Clinicopathologic and Molecular Features in Never-Smokers

In a subset of lung adenocarcinomas the epidermal growth factor receptor (EGFR) is activated by kinase domain mutations and/or gene amplification, but the interaction between the two types of abnormalities is complex and unclear. We selected to study 99 consecutive never-smoking women of East Asian...

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Hauptverfasser: Sholl, Lynette M., Yeap, Beow Y., Iafrate, A. John, Holmes-Tisch, Alison J., Chou, Yi-Ping, Wu, Ming-Tsang, Goan, Yih-Gang, Su, Li, Benedittini, Elisa, Yu, Jian, Loda, Massimo, Jänne, Pasi A., Christiani, David C., Chirieac, Lucian R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783286/
https://ncbi.nlm.nih.gov/pubmed/19826035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2477
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