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Proinflammatory cytokines oppose opioid induced acute and chronic analgesia
Spinal proinflammatory cytokines are powerful pain-enhancing signals that contribute to pain following peripheral nerve injury (neuropathic pain). Recently, one proinflammatory cytokine, interleukin-1, was also implicated in the loss of analgesia upon repeated morphine exposure (tolerance). In contr...
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主要な著者: | , , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2008
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783238/ https://ncbi.nlm.nih.gov/pubmed/18599265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2008.05.004 |
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