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Proinflammatory cytokines oppose opioid induced acute and chronic analgesia

Spinal proinflammatory cytokines are powerful pain-enhancing signals that contribute to pain following peripheral nerve injury (neuropathic pain). Recently, one proinflammatory cytokine, interleukin-1, was also implicated in the loss of analgesia upon repeated morphine exposure (tolerance). In contr...

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書誌詳細
主要な著者: Hutchinson, Mark R., Coats, Benjamen D., Lewis, Susannah S., Zhang, Yingning, Sprunger, David B., Rezvani, Niloofar, Baker, Eric M., Jekich, Brian M., Wieseler, Julie L., Somogyi, Andrew A., Martin, David, Poole, Stephen, Judd, Charles M., Maier, Steven F., Watkins, Linda R.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783238/
https://ncbi.nlm.nih.gov/pubmed/18599265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2008.05.004
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