Isolevuglandins covalently modify phosphatidylethanolamines in vivo: detection and quantitative analysis of hydroxylactam adducts

Levuglandins (LGs) and isolevuglandins (isoLGs, also called “isoketals” or “isoKs”) are extraordinarily reactive products of cyclooxygenase and free radical-induced oxidation of arachidonates. We now report the detection in vivo and quantitative analysis of LG/isoLG adducts that incorporate the amin...

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Hauptverfasser: Li, Wei, Laird, James M., Lu, Liang, Roychowdhury, Sanjoy, Nagy, Laura E., Zhou, Rong, Crabb, John W., Salomon, Robert G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783230/
https://ncbi.nlm.nih.gov/pubmed/19751823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.09.003
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