Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations

We have previously reported that sulindac, a non-steroidal anti-inflammatory drug, inhibited tumor formation in the small intestine but increased tumors in the colon of Apc(Min/)(+) mice, a model of human familial adenomatous polyposis. To further explore intestinal regional responses, we studied ef...

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Hlavní autoři: Itano, Osamu, Yang, Kan, Fan, Kunhua, Kurihara, Naoto, Shinozaki, Hiroharu, Abe, Sadanori, Jin, Bo, Gravaghi, Claudia, Edelmann, Winfried, Augenlicht, Leonard, Kopelovich, Levy, Kucherlapati, Raju, Lamprecht, Sergio, Lipkin, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Cancer Prevention
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783002/
https://ncbi.nlm.nih.gov/pubmed/19755659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp200
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