Pediatric Antihypertensive Trial Failures: Analysis of Endpoints and Dose Range

Historically, drugs prescribed for children have not been studied in pediatric populations. Since 1997, however, a 6-month extension of marketing rights is granted if manufacturers conduct Food and Drug Administration (FDA)-defined pediatric trials. In nearly half the drugs studied, there were unexp...

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Main Authors: Benjamin, Daniel K., Smith, P. Brian, Jadhav, Pravin, Gobburu, Jogarao V., Murphy, M. Dianne, Hasselblad, Vic, Baker-Smith, Carissa, Califf, Robert M., Li, Jennifer S.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782749/
https://ncbi.nlm.nih.gov/pubmed/18332283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.107.108886
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