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A new equivalence based metric for predictive check to qualify mixed-effects models
The main objective of any modeling exercise is to provide a rationale for effective decision making during drug development. The aim of the current simulation experiment was to evaluate the properties of predictive check as a covariate model qualification technique and, more importantly, to introduc...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer-Verlag
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751255/ https://ncbi.nlm.nih.gov/pubmed/16353930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj070353 |
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