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A new equivalence based metric for predictive check to qualify mixed-effects models

The main objective of any modeling exercise is to provide a rationale for effective decision making during drug development. The aim of the current simulation experiment was to evaluate the properties of predictive check as a covariate model qualification technique and, more importantly, to introduc...

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Detalhes bibliográficos
Main Authors: Jadhav, Pravin R., Gobburu, Jogarao V. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751255/
https://ncbi.nlm.nih.gov/pubmed/16353930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj070353
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