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Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies
To identify potential determinants of substrate selectivity in serotonin (5-HT) transporters (SERT), models of human and Drosophila serotonin transporters (hSERT, dSERT) were built based on the leucine transporter (LeuT(Aa)) structure reported by Yamashita et al. (Nature 2005;437:215–223), PBDID 2A6...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782712/ https://ncbi.nlm.nih.gov/pubmed/18704946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22178 |
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