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CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock

Heterodimers of CLOCK and BMAL1, bHLH-PAS transcription factors, are believed to be the major transcriptional regulators of the circadian clock mechanism in mammals. However, a recent study shows that CLOCK-deficient mice continue to exhibit robust behavioral and molecular rhythms. Here we report th...

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Autors principals: DeBruyne, Jason P, Weaver, David R, Reppert, Steven M
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782643/
https://ncbi.nlm.nih.gov/pubmed/17417633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1884
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