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Solution Structure of an Archaeal RNase P Binary Protein Complex. Formation of the 30-kDa Complex Between Pyrococcus furiosus RPP21 and RPP29 is Accompanied by Coupled Protein Folding, and Highlights Critical Features for Protein-Protein and Protein-RNA Interactions

RNase P is a ribonucleoprotein (RNP) enzyme that catalyzes the Mg(2+)-dependent 5’ maturation of precursor tRNAs. In all domains of life, it is a ribozyme: the RNase P RNA (RPR) component has been demonstrated to be responsible for catalysis. However, the number of RNase P protein subunits (RPPs) va...

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Detalhes bibliográficos
Main Authors: Xu, Yiren, Amero, Carlos D., Pulukkunat, Dileep K., Gopalan, Venkat, Foster, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782587/
https://ncbi.nlm.nih.gov/pubmed/19733182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.068
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