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DNA Sequence Modulates the Conformation of the Food Mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the Recognition Sequence of the NarI Restriction Enzyme

The conformations of C8-dG adducts of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) positioned in the C-X(1)-G, G-X(2)-C, and C-X(3)-C contexts in the C-G(1)-G(2)-C-G(3)-C-C recognition sequence of the NarI restriction enzyme were compared, using the oligodeoxynucleotides 5′-d(CTCXGCGCCATC)-3′·5′-d(G...

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Main Authors: Wang, Feng, Elmquist, C. Eric, Stover, James S., Rizzo, Carmelo J., Stone, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782574/
https://ncbi.nlm.nih.gov/pubmed/17602664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700361u
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