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Base-Displaced Intercalated Structure of the Food Mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the Recognition Sequence of the NarI Restriction Enzyme, a Hotspot for −2 bp Deletions

The solution structure of the oligodeoxynucleotide 5′-d(CTCGGCXCCATC)-3′·5′-d(GATGGCGCCGAG)-3′ containing the heterocyclic amine 8-[(3-methyl-3H-imidazo[4,5-f]quinolin-2-yl)amino]-2′-deoxyguanosine adduct (IQ) at the third guanine in the NarI restriction sequence, a hot spot for −2 bp frameshifts, i...

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Библиографические подробности
Главные авторы: Wang, Feng, DeMuro, Nicholas E., Elmquist, C. Eric, Stover, James S., Rizzo, Carmelo J., Stone, Michael P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692337/
https://ncbi.nlm.nih.gov/pubmed/16881637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja062004v
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