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Antitumor Agents. 269. Non-Aromatic Ring-A Neo-tanshinlactone Analog, TNO, as a New Class of Potent Antitumor Agents

Tetrahydroneotanshinlactone (TNT) and tetrahydronaphthalene-1-ol (TNO) derivatives were designed, synthesized, and evaluated for cytotoxic activity. The TNO derivatives were found to be a promising novel class of in vitro antitumor agents. The cyclohexene ring-A could dramatically affect the antitum...

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Dades bibliogràfiques
Autors principals: Dong, Yizhou, Shi, Qian, Nakagawa-Goto, Kyoko, Wu, Pei-Chi, Bastow, Kenneth F., Morris-Natschke, Susan L., Lee, Kuo-Hsiung
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782515/
https://ncbi.nlm.nih.gov/pubmed/19819136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.09.092
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