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4E-BP1 is a target of Smad4 essential for TGFβ-mediated inhibition of cell proliferation
Assembly of the multi-subunit eukaryotic translation initiation factor-4F (eIF4F) is critical for protein synthesis and cell growth and proliferation. eIF4F formation is regulated by the translation-inhibitory protein 4E-BP1. While proliferation factors and intracellular pathways that impinge upon 4...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782102/ https://ncbi.nlm.nih.gov/pubmed/19834456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.291 |
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