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Ca(2+)-dependent Conformational Changes in a C-terminal Cytosolic Domain of Polycystin-2
The PKD1 and PKD2 genes are the genes that are mutated in patients suffering from autosomal dominant polycystic kidney disease. The human PKD2 gene codes for a 968-amino acid long membrane protein called polycystin-2 that represents a cation channel whose activity can be regulated by Ca(2+) ions. By...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782030/ https://ncbi.nlm.nih.gov/pubmed/19546223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025635 |
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