The Thioxotriazole Copper(II) Complex A0 Induces Endoplasmic Reticulum Stress and Paraptotic Death in Human Cancer Cells

The copper(II) complex A0 induces a type of non-apoptotic cell death also known as paraptosis. Paraptosis involves extensive endoplasmic reticulum vacuolization in the absence of caspase activation. A wide panel of human cancer cell lines was used to demonstrate differences in cytotoxicity by the pa...

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Detalhes bibliográficos
Main Authors: Tardito, Saverio, Isella, Claudio, Medico, Enzo, Marchiò, Luciano, Bevilacqua, Elena, Hatzoglou, Maria, Bussolati, Ovidio, Franchi-Gazzola, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782024/
https://ncbi.nlm.nih.gov/pubmed/19561079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026583
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