載入...

Mice Deficient in Both Mn Superoxide Dismutase and Glutathione Peroxidase-1 Have Increased Oxidative Damage and a Greater Incidence of Pathology but No Reduction in Longevity

To test the impact of increased mitochondrial oxidative stress as a mechanism underlying aging and age-related pathologies, we generated mice with a combined deficiency in two mitochondrial-localized antioxidant enzymes, Mn superoxide dismutase (MnSOD) and glutathione peroxidase-1 (Gpx-1). We compar...

全面介紹

Na minha lista:

書目詳細資料
Main Authors:	Zhang, Yiqiang, Ikeno, Yuji, Qi, Wenbo, Chaudhuri, Asish, Li, Yan, Bokov, Alex, Thorpe, Suzanne R., Baynes, John W., Epstein, Charles, Richardson, Arlan, Van Remmen, Holly
格式:	Artigo
語言:	Inglês
出版:	Oxford University Press 2009
主題:	Journal of Gerontology: Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2781787/ https://ncbi.nlm.nih.gov/pubmed/19776219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glp132
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

Mice Deficient in Both Mn Superoxide Dismutase and Glutathione Peroxidase-1 Have Increased Oxidative Damage and a Greater Incidence of Pathology but No Reduction in Longevity

相似書籍