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Quantifying cancer progression with conjunctive Bayesian networks
Motivation: Cancer is an evolutionary process characterized by accumulating mutations. However, the precise timing and the order of genetic alterations that drive tumor progression remain enigmatic. Results: We present a specific probabilistic graphical model for the accumulation of mutations and th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781752/ https://ncbi.nlm.nih.gov/pubmed/19692554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp505 |
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