A Mycobacterial Cyclic AMP Phosphodiesterase That Moonlights as a Modifier of Cell Wall Permeability

Mycobacterium tuberculosis utilizes many mechanisms to establish itself within the macrophage, and bacterially derived cAMP is important in modulating the host cellular response. Although the genome of M. tuberculosis is endowed with a number of mammalian-like adenylyl cyclases, only a single cAMP p...

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Bibliographic Details
Main Authors: Podobnik, Marjetka, Tyagi, Richa, Matange, Nishad, Dermol, Urška, Gupta, Arun K., Mattoo, Rohini, Seshadri, Kothandaraman, Visweswariah, Sandhya S.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781701/
https://ncbi.nlm.nih.gov/pubmed/19801656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049635
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