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Exonuclease Function of Human Mre11 Promotes Deletional Nonhomologous End Joining
DNA double-stranded breaks (DSBs) are lethal if not repaired and are highly mutagenic if misrepaired. Nonhomologous end joining (NHEJ) is one of the major DSB repair pathways and can rejoin the DSB ends either precisely or with mistakes. Recent evidence suggests the existence of two NHEJ subpathways...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781611/ https://ncbi.nlm.nih.gov/pubmed/19744924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059444 |
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