Rescue of a Trafficking Defective Human Pacemaker Channel via a Novel Mechanism: ROLES OF Src, Fyn, AND Yes TYROSINE KINASES

Therapeutic strategies such as using channel blockers and reducing culture temperature have been used to rescue some long QT-associated voltage-gated potassium Kv trafficking defective mutant channels. A hyperpolarization-activated cyclic nucleotide-gated HCN4 pacemaker channel mutant (D553N) has be...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lin, Yen-Chang, Huang, Jianying, Kan, Hong, Frisbee, Jefferson C., Yu, Han-Gang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Membrane Transport, Structure, Function, and Biogenesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781598/
https://ncbi.nlm.nih.gov/pubmed/19748888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.039180
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