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Evidence That Integrin αIIbβ3-dependent Interaction of Mast Cells with Fibrinogen Exacerbates Chronic Inflammation

Integrin αIIbβ3 is expressed in mast cells as well as in megakaryocytes/platelets. A recent study has shown that surface expression levels of integrin αVβ3 are elevated in integrin αIIb-deficient bone marrow-derived mast cells (BMMCs) as compared with wild-type (WT) counterparts, but the underlying...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Oki, Toshihiko, Eto, Koji, Izawa, Kumi, Yamanishi, Yoshinori, Inagaki, Naoki, Frampton, Jon, Kitamura, Toshio, Kitaura, Jiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781542/
https://ncbi.nlm.nih.gov/pubmed/19755424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.030213
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