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Designer Monotransregulators Provide a Basis for a Transcriptional Therapy for de novo Endocrine-Resistant Breast Cancer
The main circulating estrogen hormone 17β-estradiol (E2) contributes to the initiation and progression of breast cancer. Estrogen receptors (ERs), as transcription factors, mediate the effects of E2. Ablation of the circulating E2 and/or prevention of ER functions constitute approaches for ER-positi...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
ScholarOne
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781301/ https://ncbi.nlm.nih.gov/pubmed/19946606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2009.00107 |
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