ON/OFF and Beyond - A Boolean Model of Apoptosis

Apoptosis is regulated by several signaling pathways which are extensively linked by crosstalks. Boolean or logical modeling has become a promising approach to capture the qualitative behavior of such complex networks. Here we built a large-scale literature-based Boolean model of the central intrins...

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Detalhes bibliográficos
Main Authors: Schlatter, Rebekka, Schmich, Kathrin, Avalos Vizcarra, Ima, Scheurich, Peter, Sauter, Thomas, Borner, Christoph, Ederer, Michael, Merfort, Irmgard, Sawodny, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781112/
https://ncbi.nlm.nih.gov/pubmed/20011108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000595
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