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Effects of let-7 microRNA on Cell Growth and Differentiation of Papillary Thyroid Cancer

Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy and RET/PTC rearrangements represent key genetic events frequently associated to this cancer, enhancing proliferation and dedifferentiation by activation of the RET/PTC-RAS-BRAF-mitogen-activated protein kinase (MAPK) pathway....

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Detalhes bibliográficos
Main Authors: Ricarte-Filho, Júlio Cezar Marques, Fuziwara, Cesar Seigi, Yamashita, Alex Shimura, Rezende, Eloiza, da-Silva, Marley Januário, Kimura, Edna Teruko
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781070/
https://ncbi.nlm.nih.gov/pubmed/19956384
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