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Dendritic Cells Loaded with Tumor Antigens and a Dual Immunostimulatory and Anti-Interleukin 10-Specific Small Interference RNA Prime T Lymphocytes against Leukemic Cells

Vaccines using dendritic cells (DCs) harboring leukemic antigens to stimulate T cells is a possible treatment of acute myeloid leukemia (AML). Limitations of breaking tolerance to leukemic cells and lack of specific activation of T cell-mediated cytotoxicity may explain the discouraging clinical res...

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Hlavní autoři: Iversen, Per O, Semaeva, Elvira, Sorensen, Dag R, Wiig, Helge, Sioud, Mouldy
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781069/
https://ncbi.nlm.nih.gov/pubmed/19956385
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