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Immunostimulatory bacterial DNA sequences activate dendritic cells and promote priming and differentiation of CD8(+) T cells

CD8(+) T lymphocytes producing high levels of interferon‐γ (IFN‐γ) and expressing antigen specific cytotoxic activity are effectively induced after plasmid DNA vaccination and mediate protection against several intracellular micro‐organisms. Recent evidence suggests that the priming of CD8(+) T‐cell...

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Detalhes bibliográficos
Principais autores: Tascon, R E, Ragno, S, Lowrie, D B, Colston, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327138/
https://ncbi.nlm.nih.gov/pubmed/10651934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00941.x
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