Is macrophage death on the field of battle essential to victory, or a tactical weakness in immunity against tuberculosis?

Por Lowrie, D B
Publicado em 1990

A single mycobacterial protein (hsp 65) expressed by a transgenic antigen-presenting cell vaccinates mice against tuberculosis.

Por Silva, C L, Lowrie, D B
Publicado em 1994

Analytical subcellular fractionation of alveolar macrophages from normal and BCG-vaccinated rabbits with particular reference to heterogeneity of hydrolase-containing granules.

Por Lowrie, D B, Andrew, P W, Peters, T J
Publicado em 1979

Major histocompatibility complex non-restricted presentation to CD4+ T lymphocytes of Mycobacterium leprae heat-shock protein 65 antigen by macrophages transfected with the mycobac...

Por Silva, C L, Lukacs, K, Lowrie, D B
Publicado em 1993

Effects of recombinant interferon-gamma and chemotherapy with isoniazid and rifampicin on infections of mouse peritoneal macrophages with Listeria monocytogenes and Mycobacterium m...

Por Khor, M., Lowrie, D. B., Mitchison, D. A.
Publicado em 1986

Growth hormone activation of human monocytes for superoxide production but not tumor necrosis factor production, cell adherence, or action against Mycobacterium tuberculosis.

Por Warwick-Davies, J, Lowrie, D B, Cole, P J
Publicado em 1995

Immunostimulatory bacterial DNA sequences activate dendritic cells and promote priming and differentiation of CD8(+) T cells

Por Tascon, R E, Ragno, S, Lowrie, D B, Colston, M J
Publicado em 2000

Strains of Mycobacterium tuberculosis differ in susceptibility to reactive nitrogen intermediates in vitro.

Por O'Brien, L, Carmichael, J, Lowrie, D B, Andrew, P W
Publicado em 1994

Recombinant interferon-gamma and chemotherapy with isoniazid and rifampicin in experimental murine tuberculosis.

Por Khor, M., Lowrie, D. B., Coates, A. R., Mitchison, D. A.
Publicado em 1986

Hydrogen peroxide and superoxide release by alveolar macrophages from normal and BCG-vaccinated guinea-pigs after intravenous challenge with Mycobacterium tuberculosis.

Por Jackett, P. S., Andrew, P. W., Aber, V. R., Lowrie, D. B.
Publicado em 1981

The contribution of hydrogen peroxide resistance to virulence of Mycobacterium tuberculosis during the first six days after intravenous infection of normal and BCG-vaccinated guine...

Por Jackett, P. S., Aber, V. R., Mitchison, D. A., Lowrie, D. B.
Publicado em 1981

Characterization of T cells that confer a high degree of protective immunity against tuberculosis in mice after vaccination with tumor cells expressing mycobacterial hsp65.

Por Silva, C L, Silva, M F, Pietro, R C, Lowrie, D B
Publicado em 1996

Protection against tuberculosis by passive transfer with T-cell clones recognizing mycobacterial heat-shock protein 65.

Por Silva, C L, Silva, M F, Pietro, R C, Lowrie, D B
Publicado em 1994

Induction of synthesis of components of the hydrogen peroxide-generating oxidase during activation of the human monocytic cell line U937 by interferon-gamma.

Por Andrew, P W, Robertson, A K, Lowrie, D B, Cross, A R, Jones, O T
Publicado em 1987

Activation of mouse peritoneal macrophages by maintenance in serum-free medium.

Por Walker, L, Lowrie, D B, Barclay, R, Dixon, G, Saunders, K, Andrew, P W
Publicado em 1991

Apparent killing of Mycobacterium tuberculosis by cytokine-activated human monocytes can be an artefact of a cytotoxic effect on the monocytes.

Por Warwick-Davies, J, Dhillon, J, O'Brien, L, Andrew, P W, Lowrie, D B
Publicado em 1994

Monocyte antimycobacterial activity before and after Mycobacterium bovis BCG vaccination in Chingleput, India, and London, United Kingdom.

Por Cheng, S H, Walker, K B, Lowrie, D B, Mitchison, D A, Swamy, R, Datta, M, Prabhakar, R
Publicado em 1993

The pattern of mycobacterial antigen recognition in sera from Mantoux-negative individuals is essentially unaffected by bacille Calmette-Guérin (BCG) vaccination in either south In...

Por Das, S, Cheng, S H, Lowrie, D B, Walker, K B, Mitchison, D A, Vallishayee, R S, Narayanan, P R
Publicado em 1992

Demonstration of increased anti-mycobacterial activity in peripheral blood monocytes after BCG vaccination in British school children.

Por Cheng, S H, Walker, L, Poole, J, Aber, V R, Walker, K B, Mitchison, D A, Lowrie, D B
Publicado em 1988

Protection against tuberculosis by bone marrow cells expressing mycobacterial hsp65.

Por Silva, C L, Pietro, R L, Januario, A, Bonato, V L, Lima, V M, da Silva, M F, Lowrie, D B
Publicado em 1995