Insulin Resistance and Altered Systemic Glucose Metabolism in Mice Lacking Nur77

OBJECTIVE: Nur77 is an orphan nuclear receptor with pleotropic functions. Previous studies have identified Nur77 as a transcriptional regulator of glucose utilization genes in skeletal muscle and gluconeogenesis in liver. However, the net functional impact of these pathways is unknown. To examine th...

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Hauptverfasser: Chao, Lily C., Wroblewski, Kevin, Zhang, Zidong, Pei, Liming, Vergnes, Laurent, Ilkayeva, Olga R., Ding, Shi Ying, Reue, Karen, Watt, Matthew J., Newgard, Christopher B., Pilch, Paul F., Hevener, Andrea L., Tontonoz, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2009
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780886/
https://ncbi.nlm.nih.gov/pubmed/19741162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0763
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