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Transcriptional regulator Id2 controls survival of hepatic NKT cells

Natural killer T cells expressing an invariant T-cell receptor (iNKT) regulate activation of both innate and adaptive immunity in many contexts. iNKT cells accumulate in the liver and rapidly produce prodigious amounts of numerous cytokines upon activation, impacting the immune response to viral inf...

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Autors principals: Monticelli, Laurel A., Yang, Yang, Knell, Jamie, D'Cruz, Louise M., Cannarile, Michael A., Engel, Isaac, Kronenberg, Mitchell, Goldrath, Ananda W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780802/
https://ncbi.nlm.nih.gov/pubmed/19884494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908249106
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