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An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells
E proteins are basic helix-loop-helix transcription factors that regulate many key aspects of lymphocyte development. Thymocytes express multiple E proteins that are thought to provide cooperative and compensatory functions crucial for T cell differentiation. Contrary to that, we report here that th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993240/ https://ncbi.nlm.nih.gov/pubmed/20154672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1845 |
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