Functional genomic screens identify CINP as a genome maintenance protein

The DNA damage response (DDR) has a critical role in maintaining genome integrity and serves as a barrier to tumorigenesis by promoting cell-cycle arrest, DNA repair, and apoptosis. The DDR is activated not only by genotoxic agents that induce DNA damage, but also during aberrant cell-division cycle...

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Autors principals: Lovejoy, Courtney A., Xu, Xin, Bansbach, Carol E., Glick, Gloria G., Zhao, Runxiang, Ye, Fei, Sirbu, Bianca M., Titus, Laura C., Shyr, Yu, Cortez, David
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780779/
https://ncbi.nlm.nih.gov/pubmed/19889979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909345106
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