Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans

Kinesin-3 motor UNC-104/KIF1A is essential for transporting synaptic precursors to synapses. Although the mechanism of cargo binding is well understood, little is known how motor activity is regulated. We mapped functional interaction domains between SYD-2 and UNC-104 by using yeast 2-hybrid and pul...

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Dettagli Bibliografici
Autori principali: Wagner, Oliver I., Esposito, Alessandro, Köhler, Barbara, Chen, Chih-Wei, Shen, Che-Piao, Wu, Gong-Her, Butkevich, Eugenia, Mandalapu, Sailaja, Wenzel, Dirk, Wouters, Fred S., Klopfenstein, Dieter R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780759/
https://ncbi.nlm.nih.gov/pubmed/19880746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902949106
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