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NOTCH3 SIGNALING IS REQUIRED FOR THE DEVELOPMENT OF PULMONARY ARTERIAL HYPERTENSION

Notch receptor signaling is implicated in controlling smooth muscle cell proliferation and maintaining smooth muscle cells in an undifferentiated state. Pulmonary arterial hypertension is a disease characterized by excessive vascular smooth muscle cell proliferation in small pulmonary arteries, lead...

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Detalhes bibliográficos
Main Authors: Li, Xiaodong, Zhang, Xiaoxue, Leathers, Robin, Makino, Ayako, Huang, Chengqun, Parsa, Pouria, Macias, Jesus, Yuan, Jason X.-J., Jamieson, Stuart W., Thistlethwaite, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780347/
https://ncbi.nlm.nih.gov/pubmed/19855400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2021
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