Development of a drug–disease simulation model for rituximab in follicular non-Hodgkin's lymphoma

AIM: Rituximab has dramatically improved the survival of patients with non-Hodgkin's lymphomas (NHL), but the dosing regimen currently used should be optimized. However, the concentration–effect relationship of rituximab has never been described by pharmacokinetic–pharmacodynamic (PK–PD) modell...

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Detalhes bibliográficos
Main Authors: Ternant, David, Hénin, Emilie, Cartron, Guillaume, Tod, Michel, Paintaud, Gilles, Girard, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Pharmacokinetic Dynamic Relationships
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780281/
https://ncbi.nlm.nih.gov/pubmed/19843059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03494.x
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