Regulatory and pro-inflammatory phenotypes of myelin basic protein-autoreactive T cells in multiple sclerosis

MBP-specific autoreactive T cells are considered pro-inflammatory T cells and thought to play an important role in the pathogenesis of multiple sclerosis (MS). Here, we report that MBP(83–99)-specific T cells generated from MS patients (n = 7) were comprised of pro-inflammatory and regulatory subset...

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Main Authors: Hong, Jian, Li, Haiyan, Chen, Meiyue, Zang, Ying C. Q., Skinner, Sheri M., Killian, James M., Zhang, Jingwu Z.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779831/
https://ncbi.nlm.nih.gov/pubmed/19822525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxp100
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