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Characterization of the functional role of nucleotides within the URE2 IRES element and the requirements for eIF2A-mediated repression

Cap-independent initiation of translation is thought to promote protein synthesis on some mRNAs during times when cap-dependent initiation is down-regulated. However, the mechanism of cap-independent initiation is poorly understood. We have previously reported the secondary structure within the yeas...

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Detalhes bibliográficos
Main Authors: Reineke, Lucas C., Merrick, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779687/
https://ncbi.nlm.nih.gov/pubmed/19861427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1722809
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