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Sphingosine Kinase-1 Is Central to Androgen-Regulated Prostate Cancer Growth and Survival

BACKGROUND: Sphingosine kinase-1 (SphK1) is an oncogenic lipid kinase notably involved in response to anticancer therapies in prostate cancer. Androgens regulate prostate cancer cell proliferation, and androgen deprivation therapy is the standard of care in the management of patients with advanced d...

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Главные авторы: Dayon, Audrey, Brizuela, Leyre, Martin, Claire, Mazerolles, Catherine, Pirot, Nelly, Doumerc, Nicolas, Nogueira, Leonor, Golzio, Muriel, Teissié, Justin, Serre, Guy, Rischmann, Pascal, Malavaud, Bernard, Cuvillier, Olivier
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779655/
https://ncbi.nlm.nih.gov/pubmed/19956567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008048
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