Sphingosine Kinase-1 Is Central to Androgen-Regulated Prostate Cancer Growth and Survival

BACKGROUND: Sphingosine kinase-1 (SphK1) is an oncogenic lipid kinase notably involved in response to anticancer therapies in prostate cancer. Androgens regulate prostate cancer cell proliferation, and androgen deprivation therapy is the standard of care in the management of patients with advanced d...

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Bibliografiske detaljer
Main Authors: Dayon, Audrey, Brizuela, Leyre, Martin, Claire, Mazerolles, Catherine, Pirot, Nelly, Doumerc, Nicolas, Nogueira, Leonor, Golzio, Muriel, Teissié, Justin, Serre, Guy, Rischmann, Pascal, Malavaud, Bernard, Cuvillier, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779655/
https://ncbi.nlm.nih.gov/pubmed/19956567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008048
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