Sphingosine Kinase-1 Is Central to Androgen-Regulated Prostate Cancer Growth and Survival

BACKGROUND: Sphingosine kinase-1 (SphK1) is an oncogenic lipid kinase notably involved in response to anticancer therapies in prostate cancer. Androgens regulate prostate cancer cell proliferation, and androgen deprivation therapy is the standard of care in the management of patients with advanced d...

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Bibliographische Detailangaben
Hauptverfasser: Dayon, Audrey, Brizuela, Leyre, Martin, Claire, Mazerolles, Catherine, Pirot, Nelly, Doumerc, Nicolas, Nogueira, Leonor, Golzio, Muriel, Teissié, Justin, Serre, Guy, Rischmann, Pascal, Malavaud, Bernard, Cuvillier, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779655/
https://ncbi.nlm.nih.gov/pubmed/19956567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008048
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