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Titin Isoforms, Extracellular Matrix and Global Chamber Remodeling in Experimental Dilated Cardiomyopathy: Functional Implications and Mechanistic Insights

BACKGROUND: Altered titin isoforms may modify cardiac function in heart failure (HF) but the nature of isoform switches and associated functional implications are not well defined. Limited studies have reported increased compliant isoform (N2BA) expression in human systolic HF. Titin may also modula...

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Detalhes bibliográficos
Main Authors: Jaber, Wissam A., Maniu, Calin, Krysiak, Judith, Shapiro, Brian P., Meyer, Donna M., Linke, Wolfgang A., Redfield, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779561/
https://ncbi.nlm.nih.gov/pubmed/19808289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.108.768465
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