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Endosomal Toll-like receptors in autoimmunity: mechanisms for clinical diversity

The endosomal Toll-like receptors (TLR3, TLR7 and TLR9) have been implicated in the pathogenesis of autoimmune diseases. Their signaling pathways show remarkable similarities and yet the outcomes following activation of each of these TLRs lead to clinically distinct autoimmune disease phenotypes. Th...

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Autori principali: Trivedi, Sapna, Greidinger, Eric L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779546/
https://ncbi.nlm.nih.gov/pubmed/20161373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/thy.09.2
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