Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

Pregnancy-associated malaria (PAM) is caused by Plasmodium falciparum-infected erythrocytes (IEs) that bind to chondroitin sulphate A (CSA) in the placenta by PAM-associated clonally variant surface antigens (VSA). Pregnancy-specific VSA (VSA(PAM)), which include the PfEMP1 variant VAR2CSA, are targ...

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Bibliografski detalji
Glavni autori: Barfod, Lea, Bernasconi, Nadia L, Dahlbäck, Madeleine, Jarrossay, David, Andersen, Pernille Haste, Salanti, Ali, Ofori, Michael F, Turner, Louise, Resende, Mafalda, Nielsen, Morten A, Theander, Thor G, Sallusto, Federica, Lanzavecchia, Antonio, Hviid, Lars
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2007
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779471/
https://ncbi.nlm.nih.gov/pubmed/17176260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2006.05503.x
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