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Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium

The function of primary cilia depends critically on the localization of specific proteins in the ciliary membrane. A major challenge in the field is to understand protein trafficking to cilia. The Hedgehog (Hh) pathway protein Smoothened (Smo), a 7-pass transmembrane protein, moves to cilia when a l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Milenkovic, Ljiljana, Scott, Matthew P., Rohatgi, Rajat
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779247/
https://ncbi.nlm.nih.gov/pubmed/19948480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200907126
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