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A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

In animal cells, the primary cilium transduces extracellular signals through signaling receptors localized in the ciliary membrane, but how these ciliary membrane proteins are retained in the cilium is unknown. We found that ciliary membrane proteins were highly mobile, but their diffusion was imped...

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Bibliographic Details
Main Authors: Hu, Qicong, Milenkovic, Ljiljana, Jin, Hua, Scott, Matthew P., Nachury, Maxence V., Spiliotis, Elias T., Nelson, W. James
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092790/
https://ncbi.nlm.nih.gov/pubmed/20558667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191054
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